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SAM-e (S-adenosyl-methionine) is a compound that our bodies naturally produce from methionine, an amino acid found in protein-rich foods. It is distributed throughout virtually all body tissues and fluids, with concentrations decreasing with age.
Nature’s Harmony uses a natural process ISOactive SAM-e that yields 40% higher active ingredients over synthetics.SAM-e plays an essential role in more than 100 biochemical reactions in our body, contributing to the synthesis, activation and/or metabolism of hormones, neurotransmitters, nucleic acids, proteins, phospholipids and certain body tissues.
SAM-e has numerous actions within the body, including the following:
• Supports emotional health by increasing levels of serotonin, dopamine and phosphatidylserine.
• Supports joint health by providing the essential nutrients for the manufacture of cartilage. SAM-e also has analgesic and anti-inflammatory actions.
• Increases glutathione production, which is one of the most important substances in the liver for detoxification.
SAM-e is manufactured from a special yeast; however, the final product is highly purified so it does not contain any yeast organisms or particles, nor does it contain any artificial preservatives, flavours or added wheat, gluten, dairy or sugar. In regards to emotional health, studies have shown that low SAM-e levels are associated with depression. Low levels of SAM-e have been found as the single factor in the diagnosis of people with depression; in addition, SAM-e has been found to be low in those suffering depression as a by-product of other diseases, for example, fibromyalgia. Research comparing SAM-e with antidepressants or placebo found SAM-e to be effective in managing mild to moderate symptoms of depression. Long-term clinical studies on individuals suffering from osteoarthritis report that SAM-e is significantly better than placebo and as effective as non-steriodal anti-inflammatory medications (NSAIDs) for decreasing symptoms without adverse effects.
Recommended Use:
- 400–1,600 mg per day. Take in divided doses, on an empty stomach.
- 600 mg per day. Take in divided doses, on an empty stomach.
- 1200–1600 mg daily. Take in divided doses, on an empty stomach.
Contraindications: Avoid use if pregnant, breastfeeding or if you have a bipolar disorder. Consult a health care practitioner before use if you are taking prescription medications.
No known toxicity or serious side effects. Mild nausea, dry mouth and restlessness may occur rarely.
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