Contraindication: known allergy to one of the ingredients or to any flower belonging to the daisy (asteracea) family.

A few cases of prolonged bleeding time were reported. It is therefore not recommended to combine Echinacea with anticoagulant medications like Coumadin. Because Echinacea being an immune stimulant, its combination with immuno-suppressive medications like Methotrexate or Immuran is contraindicated. Echinacea is also not recommended for people suffering from leukemia or other auto-immune diseases. A study conducted in Toronto by the Motherisk Program states that Echinacea is safe during pregnancy. However, it is always best to consult a competent health professional.